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br Conclusion br Funding br Conflict of interest br Acknowle
2019-04-18
Conclusion Funding Conflict of interest Acknowledgments Introduction Ventricular tachyarrhythmias (VTs) are life-threatening events that result in hemodynamic compromise; therefore, patients often require immediate treatment such as electrical cardioversion. Despite appropriate manage
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Cholangiopathies are a group of rare diseases whose primary
2019-04-18
Cholangiopathies are a group of rare diseases whose primary or secondary target is the cholangiocyte. The onset and subsequent development processes of cholangiopathies are extremely diverse, with causes that are genetic, neoplastic, immune-mediated, idiopathic, infectious, and toxin- or drug-induce
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br An estimated million babies
2019-04-18
An estimated 15 million babies are born preterm annually. Preterm birth complications account for more than 15% of deaths in children younger than 5 years and survivors often have long-term consequences with respect to their health, growth, and psychosocial functioning. The most beneficial interve
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Despertar de la ilusi n le significa a
2019-04-18
Despertar de la “ilusión” le significa her2 inhibitors Villoro su tránsito a la crítica de las filosofías de J. Rawls yJ. Habermas, afirma que no son pertinentes para el caso de nuestra condición social y política, ya que a pesar de las diferencias importantes entre sus teorías, ambas parten “de la
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De esta manera los estados latinoamericanos se
2019-04-17
De esta manera, los estados latinoamericanos se han redefinido desde aquello que puede denominarse cautela y desconfianza. Dichos estados son la materialización de la desconfianza histórica, de la amplitud del margen del conocimiento, de la apreciación de que no todo va bien y por supuesto, de una “
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Los gobiernos actuales de Bolivia y Ecuador que fueron
2019-04-17
Los gobiernos actuales de Bolivia y Ecuador, que fueron activos impulsores de los cambios constitucionales, tienen entonces simultáneamente el mandato de aprovechar (en Bolivia incluso de industrializar) los recursos naturales y de proteger los derechos de la naturaleza y los derechos de los pueblos
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br Since the launch of the Every
2019-04-17
Since the launch of the Every Newborn Action Plan (ENAP) at the World Health Assembly in 2014, and, in 2015, the launch of the UN Secretary General\'s second Global Strategy for Women\'s, Children\'s and Adolescents\' Health, there has been a renewed focus on improving newborn health globally. So
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br Introduction Incidence of oral
2019-04-17
Introduction Incidence of oral cancers accounts for ∼3% of all malignancies. Oral squamous cell carcinoma (OSCC) accounts for >95% of all malignancies in the oral cavity, and it is the fifth leading cause of cancer death in the male population in Taiwan. OSCC is treated mainly with surgery. Post
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Programmed death ligand PD L expression is a
2019-04-17
Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed
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In addition to inducing IKs dysfunction through dominant neg
2019-04-17
In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor
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br Case report In July a
2019-04-16
Case report In July 2010, a 64-year-old man visited the outpatient clinic of National Taiwan University Hospital due to progressive enlargement of right submandibular mass for months. A nasopharyngeal tumor was found by fiber optic exam, and biopsy showed a non-keratinizing undifferentiated carci
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br Anticoagulation reversal Anticoagulation may require
2019-04-16
Anticoagulation reversal Anticoagulation may require elective (as described above) or emergent reversal. Vitamin K may be administered, which substantially reduces INR within 24h; the rapidity of INR decrease depends on the route of administration and the dose [51,52]. Oral administration is pref
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Besides MPO the infiltrated neutrophils
2019-04-16
Besides MPO, the infiltrated neutrophils in IR injured liver can produce INFγ to enhance TLR4 signaling, stimulate KCs activation, and induce Th1 inflammation responses. Subsequently, M1/Th1 cycloastragenol produce INFγ to enhance neutrophil infiltration in the process of hepatic and renal IR injury
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br Conclusions Implantable monitoring devices
2019-04-16
Conclusions Implantable monitoring devices have become highly useful diagnostic tools for AT/AF [32]. However, the accuracy of the obtained diagnostic information is influenced by several factors, including the presence of non-AT/AF events, such as RNRVAS or PMT, caused by VA conduction or by sub
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br Conflict of interest br Authors contributions br
2019-04-16
Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in
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