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HF is associated with the down regulation of multiple potass
2019-06-10
HF is associated with the down-regulation of multiple potassium (K) currents (i.e., Ito, IKs, IKr, IK1, and IKATP). The only K channel that is upregulated in HF is the small conductance Ca-activated K (SK) channel. The SK channel was originally found in most neurons. The increase in Cai evoked by th
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insulin pathway Bepridil is a multichannel blocker suggestin
2019-06-10
Bepridil is a multichannel blocker, suggesting that its pharmacological effects on cardiac myocytes are exerted by blocking Na [21], Ca [22], and K [23–25] channels. It has recently been reported that bepridil has a cardioprotective effect [26] by opening ATP-dependent K insulin pathway in mitochon
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Pregnancy may induce arrhythmias due to myocardial stretch f
2019-06-10
Pregnancy may induce arrhythmias due to myocardial stretch from increased blood volume, increased sympathetic tone due to increased sensitivity of adrenergic receptors, and the effect of hormones such as mst1 kinase and progesterone [5]. In most cases of pregnancy-induced arrhythmia, the arrhythmia
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br The Ministerial Conference on in Asia
2019-06-10
The Ministerial Conference on in Asia and the Pacific is taking place on Nov 24–28, 2014, in Bangkok, Thailand. In recognition of this and parallel plans from the UN Economic Commission for Africa for a Ministerial Conference on CRVS for African countries, to be held in Côte d\'Ivoire in February
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OF-1 Supplier Desde otro contexto Andy Hargreaves planteaba
2019-06-10
Desde otro contexto, Andy Hargreaves planteaba en el año 2000 que las relaciones de la familia y la escuela también se tensionan en torno OF-1 Supplier la estandarización: En el contexto internacional, tal como lo hemos ejemplificado del sistema escolar formal, Mathew Malkan plantea que los proceso
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Esta institucionalizaci n penetr en la sociedad por
2019-06-10
Esta institucionalización penetró en la sociedad, por lo que sus integrantes fueron apartándose de las prácticas políticas que pudiesen identificarlos como comunistas. En la etapa posdemocrática, el uso de palabras como filocomunistas o pro-comunistas, convivió con la instauración de los gobiernos e
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Esta institucionalizaci n penetr en la sociedad por
2019-06-10
Esta institucionalización penetró en la sociedad, por lo que sus integrantes fueron apartándose de las prácticas políticas que pudiesen identificarlos como comunistas. En la etapa posdemocrática, el uso de palabras como filocomunistas o pro-comunistas, convivió con la instauración de los gobiernos e
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A critical link exists between awareness of risk the presenc
2019-06-10
A critical link exists between awareness of risk, the presence of disease, and steps taken by the patient and clinician to change the natural history of disease. Chronic illnesses such as diabetes mellitus, dyslipidaemia, anaemia and a multitude of endocrinological and rheumatological diseases are r
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br Materials and methods br Results br Discussion
2019-06-10
Materials and methods Results Discussion Osteosarcoma derives from primitive bone-forming mesenchymal cells and is the most common type of primary bone malignancy [20]. Over the past few decades, the introduction of combinatorial chemotherapy has improved the 5-year overall survival rate of
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Introduction The assessment of hormonal receptor HR and
2019-06-06
Introduction The assessment of hormonal receptor (HR) and human epidermal growth factor receptor-2 (HER2) status by immunohistochemistry (IHC) groups breast cancer into three major subtypes: 1) luminal-like subtype (HR positive/HER2 negative); 2) HER2 subtype (HER2 positive and HR negative/positive
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MIP binds to three different receptors CCR
2019-06-06
MIP-1α binds to three different receptors: CCR1, CCR5 and CCR9. CCR1 and CCR5 are expressed on MM sorafenib tosylate and stromal cells. Inhibitors to CCR1 and CCR5 have been used to delineate the roles of each receptor in the myeloma bone marrow microenvironment[69]. Menu and colleagues demonstrate
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p-Cresyl sulfate WHO estimates that of people with tuberculo
2019-06-06
WHO estimates that 30–50% of people with tuberculosis are untreated, in part because of underdiagnosis. Patients with undiagnosed (or diagnosed and untreated) tuberculosis are most likely to transmit infection, so strategies to reduce disease burden should focus on improving the pathway to care for
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Univariate analysis for overall survival revealed
2019-06-06
Univariate analysis for overall survival revealed that age (≤, >50 years), menopausal status, T-N stage, and histological tumor size were statistically significant factors for survival. Menopausal status was determined after two years of amenorrhea. In post-menopausal women, the disease-free surviva
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kanamycin Editorial opinion piece Many patients with advance
2019-06-06
Editorial/opinion piece Many patients with advanced cancer will develop bone metastases and associated complications, including severe pain and debilitating skeletal-related events (SREs), which require radiotherapy, surgery or changes to antineoplastic regimens [1–3]. Fortunately, there are effect
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br The achievement of an AIDS free future will surely
2019-06-06
The achievement of an AIDS-free future will surely be a priority discussion topic at the upcoming International AIDS Society conference in Melbourne, Australia. The discovery that antiretroviral therapy (ART) limits HIV transmission follows several years of steady progress in controlling the epide
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