• In addition to inducing IKs dysfunction through dominant neg

  2019-04-17

  

  In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor

• br Case report In July a

  2019-04-16

  

  Case report In July 2010, a 64-year-old man visited the outpatient clinic of National Taiwan University Hospital due to progressive enlargement of right submandibular mass for months. A nasopharyngeal tumor was found by fiber optic exam, and biopsy showed a non-keratinizing undifferentiated carci

• br Anticoagulation reversal Anticoagulation may require

  2019-04-16

  

  Anticoagulation reversal Anticoagulation may require elective (as described above) or emergent reversal. Vitamin K may be administered, which substantially reduces INR within 24h; the rapidity of INR decrease depends on the route of administration and the dose [51,52]. Oral administration is pref

• Besides MPO the infiltrated neutrophils

  2019-04-16

  

  Besides MPO, the infiltrated neutrophils in IR injured liver can produce INFγ to enhance TLR4 signaling, stimulate KCs activation, and induce Th1 inflammation responses. Subsequently, M1/Th1 cycloastragenol produce INFγ to enhance neutrophil infiltration in the process of hepatic and renal IR injury

• br Conclusions Implantable monitoring devices

  2019-04-16

  

  Conclusions Implantable monitoring devices have become highly useful diagnostic tools for AT/AF [32]. However, the accuracy of the obtained diagnostic information is influenced by several factors, including the presence of non-AT/AF events, such as RNRVAS or PMT, caused by VA conduction or by sub

• br Conflict of interest br Authors contributions br

  2019-04-16

  

  Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in

• br Conclusions br Conflict of interest br

  2019-04-16

  

  Conclusions Conflict of interest Introduction Radiofrequency (RF) catheter ablation is an established method of therapy for symptomatic supraventricular tachycardia (SVT). It has gained widespread acceptance for the treatment of accessory pathways in pediatric SVTs [1]. Accessory pathways a

• Respecto a las libertades propuestas por

  2019-04-16

  

  Respecto rna helicase las libertades propuestas por Dahl (expresión, información y asociación) señala que no son suficientes, podrían tenerse en cuenta otras, o explicitar sus alcances, lo cual constituye un problema difícil de asumir. Él mismo no propone una lista de libertades. En todo caso, el én

• Esta idea se reforz con uno de

  2019-04-16

  

  Esta idea se reforzó con uno de los elementos identitarios oficiales de la organización, su propio escudo. La comil tomó cuatro de las características reconocibles del pgt histórico; es decir, las siglas, la estrella, la hoz y el martillo, y el círculo que enmarcó todos estos símbolos, mismos que de

• To determine the discriminatory power

  2019-04-15

  

  To determine the discriminatory power of the ischiopubic index, the ROC curve was used (Fig. 3). The area under the curve for sex differentiation was 83.5% for the ischiopubic index. In the study beauty spot with a differentiation point of 100.47°, sensitivity of 82%, specificity of 78%, and accurac

• Chronic hepatitis B virus HBV infection is

  2019-04-15

  

  Chronic thyroid hormone receptor virus (HBV) infection is prevalent in many Asian countries, notwithstanding three decades of universal hepatitis B vaccination programs. The invention of nucleos(t)ide analogs (NUCs) was a breakthrough in the treatment of chronic hepatitis B (CHB). However, HBV cont

• Inappropriate shocks can be avoided in the following ways wh

  2019-04-15

  

  Inappropriate shocks can be avoided in the following ways while using a monitoring zone: (1) not setting a monitoring zone; (2) setting the VT zone at a higher rate than that of sinus tachycardia; (3) setting the VF zone at a higher rate for evaluating PAC intervals; (4) increasing the VF detection

• br Discussion False tendons are usually benign

  2019-04-15

  

  Discussion False tendons are usually benign, intraventricular myocardial structures, which may cause a musical murmur [1], rate-dependent ventricular extrasystoles, functional mitral regurgitation, or deformation of the LV cavity due to mechanical stretch and dilatation of the LV wall [1,2]. Fals

• br Conflict of Interest br Acknowledgments br

  2019-04-15

  

  Conflict of Interest Acknowledgments Introduction Human ether-a-go-go-related gene (hERG) encodes the alpha subunit of the rapidly-activating delayed-rectifier K+ channel, which plays a pivotal role in repolarization of cardiac action potentials (APs) [1]. Most of mutant hERG proteins causi

• Concern about the effects on health of chemical exposure

  2019-04-15

  

  Concern about the effects on health of chemical exposure to e-waste and e-waste recycling is increasing despite the paucity of solid research. Reported adverse effects include: fetal loss, prematurity, low birthweight, and congenital malformations; abnormal thyroid function and thyroid development;

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