• FLAG tag Peptide: Precision Epitope Tag for Recombinant P...

  2025-10-02

  The FLAG tag Peptide (DYKDDDDK) sets the benchmark for epitope tags in recombinant protein purification, offering unmatched solubility, gentle elution, and robust detection. Its integration into advanced workflows enables high-resolution studies of protein complexes and dynamic molecular mechanisms. Discover how to optimize your experimental design and troubleshoot common challenges with this essential protein purification tag peptide.

• Spermine in Advanced Cellular Metabolism and Ion Channel ...

  2025-10-01

  Explore spermine, a critical endogenous polyamine and physiological blocker of inward rectifier K+ channels, in the context of advanced cellular metabolism research. This article uniquely integrates recent discoveries in membrane fusion and polyamine signaling to uncover novel research frontiers.

• Cl-Amidine trifluoroacetate salt: Unlocking PAD4 Inhibiti...

  2025-09-30

  Cl-Amidine trifluoroacetate salt offers high selectivity and potency as a PAD4 deimination activity inhibitor, enabling precise dissection of epigenetic regulation in cancer and autoimmune disease models. Its robust performance in both in vitro and in vivo workflows streamlines histone citrullination studies, with clear advantages in immune modulation and gene expression research.

• VER 155008: Precision Inhibition of Hsp70 ATPase in Cance...

  2025-09-29

  Discover how VER 155008, a potent adenosine-derived Hsp70 inhibitor, enables precise modulation of the Hsp70 chaperone pathway in cancer research. This article uniquely dissects its mechanism, advanced apoptosis assays, and emerging roles in stress granule biology.

• Triptolide (PG490): Next-Generation Epigenetic Inhibitor ...

  2025-09-28

  Explore how Triptolide (PG490) redefines precision as an IL-2, MMP, and NF-κB inhibitor, with unique insights into its role in epigenetic reprogramming, cancer, and immune modulation. This article offers advanced analysis and practical guidance for researchers seeking novel applications of Triptolide in experimental biology.

• Torin 1: Advanced mTOR Inhibition for Precision Control o...

  2025-09-27

  Discover how Torin 1, a potent ATP-competitive mTOR inhibitor, enables precision manipulation of mTORC1 and mTORC2 signaling for advanced mTOR signaling pathway research. This article uniquely explores the intersection of mTOR inhibition, lipid metabolic engineering, and cellular fate decisions, providing insights and applications beyond conventional cancer research.

• TAK-242 (Resatorvid): Systems Pharmacology of TLR4 Inhibi...

  2025-09-26

  Explore the systems-level pharmacology of TAK-242, a selective TLR4 inhibitor, in neuroinflammation research. This in-depth analysis reveals unique translational applications and mechanistic insights into LPS-induced cytokine suppression and microglial modulation, distinguishing it from existing reviews.

• 5-Methyl-CTP: Revolutionizing mRNA Synthesis and Immunoth...

  2025-09-25

  Explore how 5-Methyl-CTP, a leading modified nucleotide for in vitro transcription, enables enhanced mRNA stability and translation efficiency. This article unveils advanced scientific insights and novel applications in mRNA synthesis and personalized immunotherapy, setting it apart from existing reviews.

• Nonivamide (Capsaicin Analog): Advanced TRPV1 Pathways in...

  2025-09-24

  Explore how Nonivamide, a leading capsaicin analog and TRPV1 receptor agonist, uniquely advances cancer cell growth inhibition and neuroimmune modulation. This article provides in-depth mechanistic insights and experimental strategies not covered in prior literature.

• Norepinephrine and epinephrine are catecholamines CA release

  2025-03-03

  

  Norepinephrine and epinephrine are catecholamines (CA) released from synaptic nerves and the adrenal gland that mediate systemic responses to nutritional stressors (Cannon and De la Paz, 1911). CA mobilize plasma glucose by suppressing insulin secretion from the pancreatic β-cell (Katada and Ui, 198

• Furthermore stress hormones can indirectly induce DNA damage

  2025-03-03

  

  Furthermore, stress hormones can indirectly induce DNA damage, for example by altering DNA repair and transcriptional regulation of the cell cycle. It has been found that stress hormones induce the up-regulation of checkpoint kinase 1 (Chk1) and checkpoint kinase 2 (Chk2) and proto-oncogene cell div

• It is important http www

  2025-03-03

  

  It is important to note that the administration of THA significantly increased the area immunostained by the anti-pVEGFR2 antibody in medial septal cholinergic neurons. The same treatment slightly increased the expression levels of VEGFR2 in cholinergic neurons; however, this change was not confirme

• Additionally regulation of GPCR heteromerization by specific

  2025-03-03

  

  Additionally, regulation of GPCR heteromerization by specific ligands may depend not only on the affinity of ligands for receptors, but also on presence of different interacting proteins co-localizing with the receptors in the specific cell, which may induce some conformational changes and contribut

• AZD0156 Western blot results showed that

  2025-03-03

  

  Western blot results showed that the expressions of SOCS1 and SOCS3 significantly increased after administration of rGas6 24h after MCAO (Fig. 7A–C p Discussion After ischemic stroke, inflammation has been shown to be an important secondary injury mediator in patients, as well as in animals (Herz

• br Conflict of interest br

  2025-03-03

  

  Conflict of interest Introduction Ovarian cancer is the most lethal gynecological malignancy, and ranks as the fifth leading cause of cancer death among women. The American Cancer Society estimates that about 22,280 new ovarian cancer cases and 14,240 deaths will occur in the United States in

15991 records 6/1067 page Previous Next First page 上5页 678910 下5页 Last page